Tag: clinical trials

adult-alone-backlit-278303

Research Shows Ketamine Could Be an Answer for Treatment-Resistant Depression

Generally speaking, most people today either know someone dealing with depression, or have struggled with depression themselves.  While many individuals can be successfully treated by a combination of medication or talk therapy, there are some who continue to experience symptoms after trying several treatments. Recent research has highlighted ketamine as a potential treatment for treatment-resistant […]

Continue Reading
072718ResQFoam

ResQFoam Study Seeks Feedback on Clinical Trial for Trauma Patients

The REVIVE clinical trial team is seeking feedback from the public on their study testing the use of RESQFOAM in severely injured trauma patients.

Continue Reading
072718ResQFoam2

Under Pressure: Mass General Clinical Trial to Test ResQFoam in Trauma Patients

Thirty-six minutes. That is the average time it takes for a person who has entered a hospital’s emergency department to reach an operating room. For a patient suffering from an exsanguinating, noncompressible abdominal hemorrhage – a severe, life-threatening trauma – that is 36 minutes of continued blood loss. What if there was a way to […]

Continue Reading
Natassi-ALS-image

New Imaging Protocol Could Vastly Accelerate Clinical Trials for New ALS Treatments

Researchers at Massachusetts General Hospital have developed a new technique for imaging the brains of patients with amyotrophic lateral sclerosis (ALS) that could vastly reduce the cost and time needed for new clinical trials—while also improving the accuracy of test results. Nazem Atassi, MD, the Associate Director of the Neurological Clinical Research Institute (NCRI) at […]

Continue Reading
53603741 - medicine doctor hand working with modern digital tablet computer interface as medical network concept

How New Biomarkers and Smartphone Apps Could Provide New Hope for ALS Patients

When a patient has strep throat, their care provider knows which antibiotics to prescribe to cure the ailment. But when a disease has no known cure, as is the case with amyotrophic lateral sclerosis (ALS), research often becomes part of clinical care. “There are still a lot of limitations in terms of what we can […]

Continue Reading
40379545 - interconnected neurons transferring information with electrical pulses.

Paganoni Advances ALS Research and Care with Technology

Technological advancements have revolutionized nearly every field of medicine from orthopedics to genetic testing. Sabrina Paganoni, MD, PhD, a clinician and researcher in the Neurological Clinical Research Institute (NCRI) at Massachusetts General Hospital, has seen firsthand the potential power and impact technology could have for amyotrophic lateral sclerosis (ALS). Paganoni is using technology to find […]

Continue Reading
NCRIgroup_650x400

Mass General Investigators on the Cutting Edge of ALS Research

May is ALS Awareness Month, intended as a time to raise awareness of and foster research for amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. ALS is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. Eventually these motor neurons die, effecting a patient’s ability to move, eat, […]

Continue Reading
Monoclonal y-shaped antibodies

Five Things To Know: New Therapy for Hereditary Angioedema

Mass General researchers recently published an article detailing a new treatment for a dangerous swelling condition called Hereditary angioedema.

Continue Reading

Patients with High-Risk Macular Degeneration Show Improvement with High-Dose Statin Treatment

Although effective treatments are available for the wet form of AMD, they are currently lacking for the more prevalent dry form. The researchers found evidence that treatment with high-dose atorvastatin (80mg) is associated with regression of lipid deposits and improvement in visual acuity, without progression to advanced disease, in high-risk AMD patients. Their findings were published in EBioMedicine — […]

Continue Reading

Antidepressant with Novel Mechanism of Action Appears Safe and Effective in Phase 1b Clinical Trial

“Our study finds that this novel compound promotes neurogenesis in a specific part of the brain, is well tolerated and may have robust antidepressant effects. If its efficacy is confirmed in larger trials, this drug could be an important new option for patients not helped by currently available medications.” –Maurizio Fava, MD. Dr. Fava is the executive director […]

Continue Reading