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Does Gout Play a Role in Preventing Alzheimer’s Disease?

Could gout—a painful form of inflammatory arthritis—play a role in preventing Alzheimer’s disease? In a large study in the United Kingdom, Mass General researchers found that patients who previously had gout had a 24% lower risk of ‪#‎Alzheimers‬ disease. Gout is caused by high levels of uric acid in the blood, which can cause complications ...

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Looking for Signs of Alzheimer’s Disease Before it Strikes

By working with a genetically linked group of 5,000 individuals in Colombia who have a significantly higher predisposition to early-onset ‪#‎Alzheimer‬’s disease than any other population in the world, Mass General researcher Yakeel T. Quiroz, PhD (pictured here), is hoping to better understand the subtle changes in the brain that take place prior to an ...

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Tanzi Named to Time’s Top 100 Most Influential People

Massachusetts General Hospital’s Dr. Rudolph Tanzi was recognized on TIME Magazine’s list of 100 Most Influential People for his pioneering work in Alzheimer’s research. In writing about him, Maria Shriver noted that Dr. Tanzi is “one of the few scientists who has committed his career to finding a cure for Alzheimer’s, and last year he ...

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This is What Tasting Looks Like

Dr. Seok-Hyun (Andy) Yun from the Wellman Center of Photomedicine at Massachusetts General Hospital was part of a global team of researchers that was able to observe live taste buds in action for the first time using a specially designed microscope system operated by Dr. Yun and his laboratory team. The study revealed that rather ...

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MGH/MIT Study Identifies Neurons Important for Inductions of Natural REM Sleep

A joint research team from Mass General and Massachusetts Institute of Technology (MIT) may be one step closer to understanding the science of sleep. Using a scanning method that can activate light-sensitive proteins, the researchers found that the activation of cholinergic neurons (those that release the neurotransmitter acetylcholine) in two structures of the brain stem are key to inducing REM ...

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A New Way to Screen for Cancer That’s as Easy as Swallowing a Pill

Researchers at Massachusetts General Hospital have developed an innovative new way to capture microscopic images of the esophagus using a capsule-sized, light-based imaging tool. This new method, which is currently being tested in clinical trials, could make it possible to screen millions of patients for precursors to esophageal cancer at a fraction of the current cost.

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Protein that Repels Immune Cells Protects Transplanted Pancreatic Islets from Rejection

A new gel-based capsule solution may hold the key to successfully transplanting insulin-producing islet cells into patients with Type 1 diabetes without the need for immunosuppressive drugs. A Mass General research study has found that by encapsulating the insulin-producing islets in gel capsules that are infused with a protein to repel key immune cells, the islet cells were protected from ...

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