Category: Mass General Research

New Polymer Gel Could Improve the Safety of Slow-Release Medications

A research team from Mass General and MIT’s Koch Institute for Integrative Cancer Research are working on a new type of polymer gel that could allow swallowed medical devices or capsules to safely act inside the body over the course of days, weeks or even months. Improving the safety of slow-release medications could open the door for devices that […]

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The Many Colors of Research At Mass General

Colorful light is used to highlight images of microfluidic devices from the Center for Engineering in Medicine at Massachusetts General Hospital:

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Grateful Patient Funds New Research into Rare But Deadly Aortic Dissection

After receiving life-saving surgery for an acute aortic dissection (AAD) at Mass General a few years ago, a former patient is helping to fund research into this rare but extremely life-threatening condition. (Above, Mark Lindsay, MD, PhD, is conducting a study to search for the genetic underpinnings of acute aortic dissection.) An AAD begins with a tear in […]

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Newly Identified Gene Variants that Modify the Onset of Huntington’s Disease Could Lead to New Therapeutics

Researchers from the Mass General Research Institute have used an innovative approach to pinpoint two locations on the human genome that influence the rate at which Huntington’s disease (HD), a debilitating neurodegenerative disorder, develops in those carrying the HD gene defect. By studying the samples from more than 4,000 HD patients, researchers were able to identify two genetic variants in […]

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MGH Diabetes Quest Takes A Big Step

Massachusetts General Hospital researcher Denise Faustman, MD, PhD, has made a promising advance in her 20-year quest to cure type 1 diabetes by receiving FDA approval to test an old tuberculosis vaccine that may also treat diabetes. READ MORE

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Reflections of Science

Afternoon clouds and surrounding buildings are reflected in the mirrored windows of the Richard B. Simches Research Building at Massachusetts General Hospital. The Simches building is home to five thematic research centers, including: The Center for Systems Biology The Center for Human Genetic Research The Center for Regenerative Medicine The Center for Computational and Integrative […]

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Mass General Research Study Suggests Active Physician Interventions Can Improve Quit Rates for Long Term Smokers

(Image Courtesy of Wikimedia Commons) A new Mass General research study suggests that physicians who take a more active role in connecting high-risk, longtime smokers with resources to help them quit can significantly improve their patients’ success at becoming smoke-free. The study found that patients who receive annual lung cancer screenings due to high-risk smoking (averaging […]

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Mass General’s History of Research Innovation

Did you know that biomedical research has been part of Massachusetts General Hospital since its founding over 200 years ago, and has led to such innovations as: The use of general anesthesia in ether The modern PET scan A bionic pancreas A chip that detects circulating tumor cells in the blood And a vaccine for […]

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Mass General Researchers Find Evidence of Neuroinflammation in Cases of Chronic Pain

A Mass General research study published earlier this year found—for the first time—evidence of neuroinflammation in the brain in patients with chronic pain. The study showed that levels of an inflammation- linked protein were elevated in regions of the brain known to be involved in the transmission of pain. The discovery could make it possible to explore new treatments […]

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Does Gender Play a Role in Fear and Anxiety?

Did you know that the levels of estrogen or testosterone that you have in your body may play a role in how much you experience anxiety? Dr. Mohammed Milad, director of the Behavioral Neuroscience Program at Mass General, has been studying how hormone levels in men and women can affect their feelings of anxiety–and the […]

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