Category: Cardiovascular Research and Heart Health

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Genetic Study Identifies Link Between Body Shape and Risk of Heart Disease and Diabetes

When you put on weight, do the pounds show up at your waistline or on your hips? The answer could have long-term implications for your risk of developing coronary heart disease (CHD) and Type 2 diabetes. Learn how Massachusetts General Hospital researchers identified a link between body shape and risk of heart disease and diabetes.

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Dr. Harald Ott in his research lab

Mass General Scientists are Growing New Hearts in the Cells of Old Ones

In the lab, Dr. Harald Ott and his colleagues have taken ghostly hearts and resurrected them as new ones. Shocked with electrical pulses, those new hearts have even started beating again.

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Scientists Grow Functional Heart Muscle

A team of researchers led by Dr. Harald Ott of the Massachusetts General Hospital Center for Regenerative Medicine have grown functional heart tissue using donated hearts stripped of their cells. This breakthrough could allow tissue patches grown from a patient’s own cells to replace cardiac tissue damaged during a heart attack.   LEARN MORE

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Human Cardiac Cells Grown on Heart ‘Scaffold’

Heart cells have been successfully grown in a human heart stripped of all cellular components by scientists at Massachusetts General Hospital. The scientists behind the work hope to create cardiac muscle to repair damaged tissue.   READ MORE

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Bariatric Surgery May Reduce Life-Threatening Heart Failure Exacerbation in Obese Patients

“We found that bariatric surgery – the most effective way to achieve substantial and sustained weight loss – was associated with a 40 percent reduction in emergency department visits and hospitalizations for heart failure exacerbation,” says Yuichi Shimada, MD, MPH, of the Mass General Cardiology Division, the lead and corresponding author of the report. “These findings are important because, while […]

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The Guide: Have a Heart

At Mass General’s Ott Laboratory for Organ Engineering and Regeneration, a small army of postdocs is drawing on the tenets of tissue engineering and stem cell science to develop “bioartificial” organs and limbs for patients in need. While it sounds like something cooked up in the pages of a Michael Crichton thriller, this novel approach has the potential to […]

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Wakefield Researcher ‘Seals’ the deal in Antarctica

Massachusetts General Hospital researcher Emmanual Buys, PhD, is part of a collaborative research team that has been working in Antarctica to study the Weddell seal, a mammal that can remain under water for longer than 70 minutes at a depth of 500 meters. Buys and his team are taking tissue samples from seals to learn […]

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Say Aaah and Swallow: This Smart Pill Could Track Your Heartbeat

“The best way to monitor vital signs like breathing and heart rate may be with a microphone that listens and transmits data from inside the body, say researchers at the MIT Lincoln Laboratory and Massachusetts General Hospital.” READ MORE

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Mass. General Team Generates Therapeutic Nitric Oxide From Air with an Electric Spark

“Once we’ve shown that this can safely be used in human patients with pulmonary hypertension – and we’ve got a clinical trial in progress right now – we’ll be able to conduct studies of inhaled NO delivered in ambulatory settings, including patients’ homes, to treat chronic pulmonary hypertension, right-sided heart failure and chronic obstructive pulmonary disease.” – Warren Zapol, MD Director, […]

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Grateful Patient Funds New Research into Rare But Deadly Aortic Dissection

After receiving life-saving surgery for an acute aortic dissection (AAD) at Mass General a few years ago, a former patient is helping to fund research into this rare but extremely life-threatening condition. (Above, Mark Lindsay, MD, PhD, is conducting a study to search for the genetic underpinnings of acute aortic dissection.) An AAD begins with a tear in […]

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