Category: Cancer Research

See recent blog posts and articles about cancer research at Massachusetts General Hospital.

Proton Therapy Controls Common Pediatric Brain Tumor With Fewer Long-Term Side Effects

“The use of proton radiotherapy to treat the most common malignant brain tumor in children is as effective as standard photon (x-ray) radiation therapy while causing fewer long-term side effects such as hearing loss and cognitive disorders, according to a study receiving online publication in Lancet Oncology. The paper from a team led by  Massachusetts General Hospital (MGH) investigators […]

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Proton Therapy Controls Common Pediatric Brain Tumor with Fewer Long-Term Side Effects

The use of proton radiotherapy to treat the most common malignant brain tumor in children is as effective as standard photon (x-ray) radiation therapy while causing fewer long-term side effects such as hearing loss and cognitive disorders, according to a study receiving online publication in Lancet Oncology. The paper from a team led by Massachusetts General Hospital (MGH) investigators […]

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New Drug Delivery System Could Reduce the Dose Needed to Treat Pancreatic Cancer

A Massachusetts General Hospital research study suggests that a nanoparticle drug-delivery system that combines two complementary types of anticancer treatment could improve outcomes for patients with pancreatic cancer and other highly treatment-resistant tumors, while decreasing treatment toxicity. The new system, which combines a light-activated nanoparticle with a molecular therapy drug, reduced the dosage required to […]

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Researchers Find a Way to Light Up Cancer Cells

Researchers at Duke University Medical Center, Massachusetts General Hospital and Massachusetts Institute of Technology have developed a probe that can find, stick to and then light up residual cancer cells, making them easier for surgeons to see. READ MORE

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After Early Roadblocks, Mass. General Researcher to be Recognized

Congratulations to distinguished Massachusetts General Hospital researcher (and longtime movie buff) Rakesh Jain, PhD, for being named a winner of the National Medal of Science. Dr. Jain, who studies tumor biology, will receive his award from President Obama later this year. “The only way I kept going was realizing in any field—really, in any human […]

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Smartphone Device Can Quickly Diagnosis Cancer

“Imagine your doctor could take some of your cells, slide them into a compartment on a smartphone and tell you if you had cancer in just an hour. You could be spared an agonizing wait for lab results. And your doctor could discuss the diagnosis and your treatment options in person. A team led by Ralph Weissleder, MD, […]

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Wakefield Researcher ‘Seals’ the deal in Antarctica

Massachusetts General Hospital researcher Emmanual Buys, PhD, is part of a collaborative research team that has been working in Antarctica to study the Weddell seal, a mammal that can remain under water for longer than 70 minutes at a depth of 500 meters. Buys and his team are taking tissue samples from seals to learn […]

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Tumor RNA Within Platelets May Help Diagnose and Classify Cancer, Identify Treatment Strategies

“By combining next-generation-sequencing gene expression profiles of platelet RNA with computational algorithms we developed, we were able to detect the presence of cancer with 96 percent accuracy,” says Bakhos Tannous, PhD, of the MGH Department of Neurology, co-senior author of the Cancer Cell paper along with investigators from VU University Medical Center in Amsterdam. READ MORE

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Mass. General Study Identifies Genomic Differences Between Breast Cancers of African American and White Women

“In addition to having a higher prevalence of triple-negative breast cancers than Caucasian women – something that has been documented in previous studies – we found that African American women with breast cancer had a significantly higher prevalence of the TP53 driver mutation, basal tumor subtype and greater genomic diversity within tumors, all of which suggest more aggressive tumor […]

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Mass General Researcher Using Scholar Award to Investigate New Imaging Technique For Breast Cancer

Lawrence Wald, PhD, and his team at the Martinos Center for Biomedical Imaging at Massachusetts General Hospital are working to advance magnetic resonance imaging (MRI) and related technologies, including magnetic particle imaging (MPI), a new method to detect small magnetic “nanoparticles” injected into the blood. Supported by an MGH Research Scholar Award, Dr. Wald and colleagues are now developing a […]

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