Category: immunology

Could There be a Link Between Herpes Virus and Alzheimer’s Disease?

A new research study from Rudolph Tanzi, PhD, and Robert Moir, PhD, researchers in the Department of Neurology at Massachusetts General Hospital, has uncovered a Jekyll and Hyde role for a naturally occurring protein in the brain most commonly associated with Alzheimer’s disease (AD). In conjunction with new findings from another research team at Icahn School of ...

Investigating the Relationship Between MRSA and the Lymphatic System

Dennis Jones, PhD, is a postdoctoral fellow in the Edwin L. Steele Labs at Massachusetts General Hospital. Dr. Jones won an award for a poster detailing the results of a research study that shows how MRSA infections contribute to recurrences of lymphedema by damaging muscle cells with bacterial toxins. Continue reading to learn more about ...

On the Hunt for New Strategies to Defeat a Killer Fungus

At first glance, Candida auris (C. auris) seems like the fungus equivalent of a comic book supervillain—at least from a human perspective. A new species of infectious fungus that arrived seemingly out of nowhere a decade ago, C. auris is resistant to all known forms of antifungal drugs, and it sticks to surfaces so well that it resists standard ...

New Tool for Predicting C. Difficile Infections Shows Promising Results

For patients in hospital and healthcare settings, a Clostridium difficile (C. difficile) infection is a complication that can result in serious complications and even death. C. difficile is caused by a bacterium and the symptoms of infection include diarrhea, fever and severe abdominal cramps. While some cases may be mild, some can be fatal—particularly in elderly, very ...

A Newly Discovered Link Between Gut Bacteria and Cholera

Researchers from Massachusetts General Hospital, Duke University and the International Centre for Diarrheal Disease Research in Dhaka, Bangladesh, have used machine learning algorithms to find patterns within communities of bacteria living in the human gut. These patterns could indicate who among the approximately one billion people at risk of cholera infection around the globe will ...

Mapping the Connections Between Allergies and the Microbiome

Why do some children develop severe allergies or autoimmune disorders when their parents have no history of either condition? Rather than looking to genetics for clues, the answer may lie in the communication that occurs between the T cells of the immune system and the bacteria in the gut, particularly at a very young age. ...

Postdoc Profile: Nabi M. Nurunnabi, PhD

Md “Nabi” Nurunnabi, PhD, is a postdoctoral research fellow at the Massachusetts General Hospital Center for Systems Biology (CSB) and the Cardiovascular Research Center (CVRC). He is also Chair of MGH Postdoc Association (MGPA). He is biomedical scientist with education and training in both academia and industry as pharmacist, chemist, and bioengineer. He is working ...

Could Controlling Inflammation Improve Cystic Fibrosis Therapies?

Today, February 28th, is the 11th annual International Rare Disease Day. This is a day for every member of the rare disease community—patients, caregivers, and researchers—to join together on behalf of all of those suffering with a rare disease. In this blog post we highlight one Massachusetts General Hospital researcher who is tackling rare disease. Fifty ...

Mass General Research Institute goes red for heart month

A Link Between Flu and Heart Attacks? Mass General Cardiologist Weighs In

New research has found yet another reason to avoid catching the flu this season- it could increase your risk of a heart attack if you’re over the age of 35. A recent study from investigators at the Institute for Clinical Evaluative Sciences and Public Health Ontario in Canada have found that you’re six times more ...

In Case You Missed it: Science Stories from Around the Web

We love good science stories here at the Mass General Research Institute and wanted to share a few of our favorites from other health and science websites. Enjoy! The best and worst analogies for CRISPR, ranked From a knockout punch to an act of God, CRISPR technology has drawn comparisons to a vast array of ...